Molecular imaging of oxidative stress using an LED-based photoacoustic imaging system
نویسندگان
چکیده
منابع مشابه
The characterization of an economic and portable LED-based photoacoustic imaging system to facilitate molecular imaging
Photoacoustic imaging (PAI) is a non-invasive, high-resolution hybrid imaging modality that combines optical excitation and ultrasound detection. PAI can image endogenous chromophores (melanin, hemoglobin, etc.) and exogenous contrast agents in different medical applications. However, most current equipment uses sophisticated and complicated OPO lasers with tuning and stability features inconsi...
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Some of the challenges in translating photoacoustic (PA) imaging to clinical applications includes limited view of the target tissue, low signal to noise ratio and the high cost of developing real-time systems. Acoustic lens based PA imaging systems, also known as PA cameras are a potential alternative to conventional imaging systems in these scenarios. The 3D focusing action of lens enables re...
متن کاملSimultaneous photoacoustic imaging technique using an acoustic imaging lens.
A simultaneous photoacoustic (PA) tomography imaging technique in multilayer samples was developed. Instead of using the PA image reconstruction methods on the basis of complex algorithms, obtaining a two-dimensional PA image in real time is available by using an acoustic lens that has the ability of parallel imaging. The imaging system can acquire the complete PA signals of high signal-to-nois...
متن کاملToward High-speed Transcranial Photoacoustic Imaging using Compact Near-infrared Pulsed LED Illumination System
Quantification of brain function is a significant milestone towards understanding of the underlying workings of the brain. Photoacoustic (PA) imaging is the emerging brain sensing modality by which the molecular light absorptive contrast can be non-invasively quantified from deep-lying tissue (~several cm). In this BRAIN initiative effort, we propose highspeed transcranial PA imaging using a no...
متن کاملA differential photoacoustic imaging system
We describe a differential photoacoustic (PA) imaging system in which almost equal intensity beams modulated 180' out of phase illuminate two regions of a sample in a PA cell. For two regions that are both optically and thermally similar and also homogeneous, the resulting signal is almost zero but if one region has a sub-surface defect this will give an increased signal. This differential sign...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2019
ISSN: 2045-2322
DOI: 10.1038/s41598-019-47599-2